# Scrapbook **URL:** \ **Category:** General\ **Created:** [September 15, 2021, 4:10pm UTC](http://forum.0xdbfb7.com/t/scrapbook/78 "2021-09-15T16:10:07Z")\ **Posts on this page:** 20\ **Page:** 4
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [December 25, 2021, 4:43am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/62 "2021-12-25T04:43:39Z")
Rotavirus vaccine intestinal side effect company tried to public domain and give away cell line but countries > In 1998, a rotavirus vaccine (RotaShield, by [Wyeth](https://en.m.wikipedia.org/wiki/Wyeth)) was licensed for use in the United States. Clinical trials in the United States, [Finland](https://en.m.wikipedia.org/wiki/Finland), and [Venezuela](https://en.m.wikipedia.org/wiki/Venezuela) had found it to be 80 to 100% effective at preventing severe diarrhea caused by rotavirus A, and researchers had detected no statistically significant serious adverse effects. The manufacturer of the vaccine, however, withdrew it from the market in 1999, after it was discovered that the vaccine may have contributed to an increased risk for [intussusception](https://en.m.wikipedia.org/wiki/Intussusception_(medical_disorder)), or bowel obstruction, in one of every 12,000 vaccinated infants.[[27]](https://en.m.wikipedia.org/wiki/Rotavirus_vaccine#cite_note-SI_42_6_Hall-27) There then followed eight years of delay until rival manufacturers were able to introduce new vaccines that were shown to be more safe and effective in children: Cool article in skeptical inquirer Magazine might be a good format for pseudoscience rhet defense ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [January 9, 2022, 4:26am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/63 "2022-01-09T04:26:06Z")
> Measured in [litres](https://en.m.wikipedia.org/wiki/Litre) (L) or cubic metres, is an inverse measure of the ‘stiffness’ of the suspension with the driver mounted in free air. It represents the volume of air that has the same stiffness as the driver’s suspension when acted on by a piston of the same area (_S_ d) as the cone. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [January 30, 2022, 1:10am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/64 "2022-01-30T01:10:05Z")
Women’s curling is really interesting! Found it on hotel TV accidentally. The fascinating aspect (and this is probably preserved in men’s curling) is that all the conversations the teammates have regarding their strategy are broadcast; all the players wear hot mics at all times. I don’t recall hearing that in other sports. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [February 20, 2022, 3:59am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/65 "2022-02-20T03:59:23Z")
> **[Code Critique: RoundRects - Apple QuickDraw Source Code](http://wg20.criticalcodestudies.com/index.php?p=%2Fdiscussion%2F80%2Fcode-critique-roundrects-apple-quickdraw-source-code)** > > Bill Atkinson was a member of the original Macintosh development team. He created Quickdraw first for the Lisa, as LisaGraf. > The conversation keeps coming back – for example, I recently saw another version of it asking about the limitations rounded rects in JavaScript + WebGL (vs Java + OpenGL). Solutions are invented, but problems don’t necessarily stay solved – they keep needing to be re-solved. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [February 28, 2022, 4:27am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/66 "2022-02-28T04:27:34Z")
> > > \”and I'm still not sure it holds up in the real world“\\Writing literature is a solo endeavour.\Modern programming is more like writing scientific literature, where multiple persons collaborate, and reading and understanding earlier work and maintaining a correct set of links to such works is half the work, if not more.\That, I think, is why literate programming doesn’t quite... > |_”and I’m still not sure it holds up in the real world“_ > > Writing literature is a solo endeavour. > > Modern programming is more like writing scientific literature, where multiple persons collaborate, and reading and understanding earlier work and maintaining a correct set of links to such works is half the work, if not more. > > That, I think, is why literate programming doesn’t quite work. It works for Mathematica notebooks, iPython notebooks and the like, but not for larger works.| ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [March 11, 2022, 3:51am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/67 "2022-03-11T03:51:02Z")
> [@0xDBFB7](#): > > As a result, for fields with the proportion of true relationships small, journals publish almost no actual relationships (shall we say, ” barely any acceptable results”). You find this in many fields. For example, in genetics, if 30 of 30,000 genes cause a disease, then R is .001 and PPV is .02. > Yet, we imagine significance tests pulling out of just such situations relationships we wouldn’t otherwise notice. We’ve deceived ourselves. Although, a followup study in a redefined field with only previously significant relationships has a much better PPV. relevant to biophysics add to paper ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [April 16, 2022, 4:56am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/68 "2022-04-16T04:56:12Z")
[http://www4.hcmut.edu.vn/~huynhqlinh/olympicvl/tailieu/physlink\_askexpert/](http://www4.hcmut.edu.vn/~huynhqlinh/olympicvl/tailieu/physlink_askexpert/) An archive of questions asked of physicists. A what-if.xkcd of yesteryear. Very nostalgic and web 1.0. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [April 26, 2022, 3:12am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/69 "2022-04-26T03:12:22Z")
_Downsampling Time Series for Visual Representation_ [https://skemman.is/bitstream/1946/15343/3/SS\_MSthesis.pdf`](https://skemman.is/bitstream/1946/15343/3/SS_MSthesis.pdf%60) A particularly well-written thesis. (via [Plotting image data in Julia is much slower than MATLAB - #18 by jmert - General Usage - JuliaLang](https://discourse.julialang.org/t/plotting-image-data-in-julia-is-much-slower-than-matlab/79660/18)) ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [April 30, 2022, 11:46pm UTC](http://forum.0xdbfb7.com/t/scrapbook/78/70 "2022-04-30T23:46:38Z")
I came across a paper a little while ago, where the core-hole lifetime broadening. I thought this was bollocks. > **[Controlling core-hole lifetime through an x-ray planar cavity](https://arxiv.org/abs/2101.11225)** > > It has long been believed that core-hole lifetime (CHL) of an atom is an intrinsic physical property, and controlling it is significant yet is very hard. Here, CHL of the 2p state of W atom is manipulated experimentally through adjusting the emission... But it seems as though these sorts of effects are indeed possible? > **[Zero-point energy](https://en.wikipedia.org/wiki/Zero-point_energy)** > > Zero-point energy (ZPE) is the lowest possible energy that a quantum mechanical system may have. Unlike in classical mechanics, quantum systems constantly fluctuate in their lowest energy state as described by the Heisenberg uncertainty principle. Therefore, even at absolute zero, atoms and molecules retain some vibrational motion. Apart from atoms and molecules, the empty space of the vacuum also has these properties. According to quantum field theory, the universe can be thought of not as is > In 1963 the [Jaynes–Cummings model](https://en.wikipedia.org/wiki/Jaynes%E2%80%93Cummings_model)[[84]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-84) was developed describing the system of a [two-level atom](https://en.wikipedia.org/wiki/Two-level_system) interacting with a quantized field mode (i.e. the vacuum) within an optical cavity. It gave nonintuitive predictions such as that an atom’s spontaneous emission could be driven by field of effectively constant frequency ([Rabi frequency](https://en.wikipedia.org/wiki/Rabi_frequency)). In the 1970s experiments were being performed to test aspects of quantum optics and showed that the rate of spontaneous emission of an atom could be controlled using reflecting surfaces.[[85]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-FOOTNOTEDrexhage1970-85)[[86]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-FOOTNOTEDrexhage1974%5B%5BCategory:Wikipedia_articles_needing_page_number_citations_from_May_2020%5D%5D%3Csup_class=%22noprint_Inline-Template_%22_style=%22white-space:nowrap;%22%3E%5B%3Ci%3E%5B%5BWikipedia:Citing_sources%7C%3Cspan_title=%22This_citation_requires_a_reference_to_the_specific_page_or_range_of_pages_in_which_the_material_appears.%20(May_2020)%22%3Epage%C2%A0needed%3C/span%3E%5D%5D%3C/i%3E%5D%3C/sup%3E-86) These results were at first regarded with suspicion in some quarters: it was argued that no modification of a spontaneous emission rate would be possible, after all, how can the emission of a photon be affected by an atom’s environment when the atom can only “see” its environment by emitting a photon in the first place? These experiments gave rise to [cavity quantum electrodynamics](https://en.wikipedia.org/wiki/Cavity_quantum_electrodynamics) (CQED), the study of effects of mirrors and cavities on radiative corrections. Spontaneous emission can be suppressed (or “inhibited”)[[87]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-87)[[88]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-88) or amplified. Amplification was first predicted by Purcell in 1946[[89]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-89) (the [Purcell effect](https://en.wikipedia.org/wiki/Purcell_effect)) and has been experimentally verified.[[90]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-FOOTNOTEGoy_et_al.1983-90) This phenomenon can be understood, partly, in terms of the action of the vacuum field on the atom.[[91]](https://en.wikipedia.org/wiki/Zero-point_energy#cite_note-FOOTNOTEMilonni1983-91) ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [May 1, 2022, 12:12am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/71 "2022-05-01T00:12:10Z")
> > ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [May 1, 2022, 5:40am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/72 "2022-05-01T05:40:46Z")
The solution to the heat-diffusion equation is a gaussian profile. But McDonald, A., K. Woodruff, Diego Gonzalez Diaz, and B. Jones. Electron Drift and Longitudinal Diffusion in High Pressure Xenon-Helium Gas Mixtures, 2019. ![Screenshot from 2022-04-30 23-42-57](http://forum.0xdbfb7.com/uploads/default/original/1X/ec11c0868d74676e0a8442ef2a7a969bfdc1b7ea.png) it’s interesting that the effect of the finite initial width is only apparent after quite some time. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [May 13, 2022, 1:16am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/73 "2022-05-13T01:16:40Z")
Nettie Maria Stevens discovered sex determination by chromosomes after getting her doctorate at **59**. [https://stemfatalepodcast.podbean.com/e/episode-069-sex-cells/](https://stemfatalepodcast.podbean.com/e/episode-069-sex-cells/) ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [May 13, 2022, 1:18am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/74 "2022-05-13T01:18:47Z")
I love how people used to regularly use solutions as laser-line filters. You see this in some fluorescence measurements, and most recently, the first observation of two-photon excitation: [https://journals-aps-org.cyber.usask.ca/prl/pdf/10.1103/PhysRevLett.9.453](https://journals-aps-org.cyber.usask.ca/prl/pdf/10.1103/PhysRevLett.9.453) > The emission from the cell, > observed at right angles to the ruby beam, was > filtered through a CuSO, solution to remove scattered red light. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [May 16, 2022, 2:57am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/75 "2022-05-16T02:57:47Z")
![Screenshot from 2022-05-14 21-29-09](http://forum.0xdbfb7.com/uploads/default/original/1X/85118a682384c63086eff6a15f42e0213e09db51.png) > ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [July 2, 2022, 6:00am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/76 "2022-07-02T06:00:12Z")
> **[udell15\_thesis.pdf](https://people.orie.cornell.edu/mru8/doc/udell15_thesis.pdf)** > > 1137.39 KB An incredible acknowledgments page. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [July 9, 2022, 7:44pm UTC](http://forum.0xdbfb7.com/t/scrapbook/78/77 "2022-07-09T19:44:17Z")
Starship project is somehow unique, but it seems like the development of the [Boeing 747](https://en.wikipedia.org/wiki/Boeing_747) > Time was so short that the 747’s full-scale [mock-up](https://en.wikipedia.org/wiki/Mock-up) was built before the factory roof above it was finished.[[40]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-Irving_p365-40) > During the final months before delivery of the first aircraft, the company had to repeatedly request additional funding to complete the project. Had this been refused, Boeing’s survival would have been threatened.[[18]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-infoplease-18)[[57]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-Irving_p437-8-57) The firm’s debt exceeded $2 billion, with the $1.2 billion owed to the banks setting a record for all companies. Allen later said, “It was really too large a project for us.”[[58]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-heppenheimer1998-58) Ultimately, the gamble succeeded, and Boeing held a monopoly in very large passenger aircraft production for many years.[[59]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-59) > Project cost $5.8 billion in 2020 dollars also interesting: > The project was designed with a new methodology called [fault tree analysis](https://en.wikipedia.org/wiki/Fault_tree_analysis), which allowed the effects of a failure of a single part to be studied to determine its impact on other systems.[[1]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-ucfc747-1) To address concerns about safety and flyability, the 747’s design included structural redundancy, redundant [hydraulic](https://en.wikipedia.org/wiki/Hydraulic_machinery) systems, quadruple main landing gear and dual control surfaces.[[29]](https://en.wikipedia.org/wiki/Boeing_747#cite_note-Sutter_p121-31-29) I really like how wiki cites page numbers. ![Screenshot from 2022-07-09 13-43-50](http://forum.0xdbfb7.com/uploads/default/original/1X/2e23f47dc67d057beaeb2ea82e32e5fb12ae86f5.png) ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [July 23, 2022, 8:26pm UTC](http://forum.0xdbfb7.com/t/scrapbook/78/78 "2022-07-23T20:26:56Z")
Bought Fava beans on a whim at the grocery store. Looking up how to cook them, I found: > As the authors state, “In favism, there are two main actors: the bean and the red cell.” Fava beans and genetic susceptibility must come together to elicit the outcome of favism. Ironically, the fava bean plant (Vicia faba; known to many as the broad bean) may have been the first plant to be domestically cultivated and produces a protein-rich bean that can be eaten hot or cold. The problem is that the bean’s protein content can include as much as 2 percent vicine and convicine, which are converted in the gut to divicine and isouramil. These highly redox proteins are likely to retard rotting of the bean, but produce reactive oxygen species (ROS) including the superoxide anion and hydrogen peroxide, which rapidly oxidize NADPH and glutathione. These molecules are normally detoxified by catalase and glutathione peroxidase, in enzymatic reactions that depend on NADPH. Because NADPH levels are very low in G6PD-deficient red cells, these undergo severe oxidative damage. A characteristic feature of favism is that intracellular and extracellular hemolysis coexist. The intracellular damage is easy to explain, whereas extracellular hemolysis occurs as complement is fixed on the cell and triggers phagocytosis. - [Deconstructing the Threat of the Fava Bean | The Hematologist | American Society of Hematology](https://ashpublications.org/thehematologist/article/doi/10.1182/hem.V15.2.8304/463044/Deconstructing-the-Threat-of-the-Fava-Bean) ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [July 30, 2022, 5:40am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/79 "2022-07-30T05:40:23Z")
> **[SPT #3: The constant singleton](https://www.engyrus.com/2015/02/spt-3-constant-singleton.html)** > > "Stupid Python Tricks" explores ways to abuse Python features for the hell of it. Stupid Python Tricks may well be perpendicular to maintain... ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [August 1, 2022, 11:48pm UTC](http://forum.0xdbfb7.com/t/scrapbook/78/80 "2022-08-01T23:48:11Z")
_ **Apple Computer, Inc. v. Mackintosh Computers Ltd.** _ [1990] 2 S.C.R. 209, is a [Supreme Court of Canada](https://en.wikipedia.org/wiki/Supreme_Court_of_Canada) case on [copyright law](https://en.wikipedia.org/wiki/Copyright_law) regarding the [copyrightability of software](https://en.wikipedia.org/wiki/Software_copyright). The Court found that programs within [ROM](https://en.wikipedia.org/wiki/Read-only_memory) silicon chips (in this case, the Autostart ROM and [Applesoft](https://en.wikipedia.org/wiki/Applesoft_BASIC) in [Apple II+](https://en.wikipedia.org/wiki/Apple_II%2B) systems) are protected under the [Copyright Act](https://en.wikipedia.org/wiki/Copyright_Act_of_Canada), and that the conversion from the [source code](https://en.wikipedia.org/wiki/Source_code) into [object code](https://en.wikipedia.org/wiki/Object_code) was a reproduction that did not alter the copyright protection of the original work. The Supreme Court declined to follow the case of _[Computer Edge Pty. Ltd. v. Apple Computer, Inc.](https://en.wikipedia.org/wiki/Computer_Edge_v._Apple)_ [[2]](https://en.wikipedia.org/wiki/Apple_Computer,_Inc._v._Mackintosh_Computers_Ltd.#cite_note-2) decided by the [High Court of Australia](https://en.wikipedia.org/wiki/High_Court_of_Australia), which had virtually identical facts. In that case, the court held that the chips contained a “sequence of electrical impulses” which could not be subject to copyright. ---
**Author:** ![0xDBFB7](http://forum.0xdbfb7.com/user_avatar/forum.0xdbfb7.com/0xdbfb7/32/7_2.png) [@0xDBFB7](http://forum.0xdbfb7.com/u/0xDBFB7)\ **Post date:** [September 7, 2022, 5:39am UTC](http://forum.0xdbfb7.com/t/scrapbook/78/81 "2022-09-07T05:39:27Z")
> **[Railway Mania](https://en.wikipedia.org/wiki/Railway_Mania)** > > Railway Mania was an instance of a stock market bubble in the United Kingdom of Great Britain and Ireland in the 1840s. It followed a common pattern: as the price of railway shares increased, speculators invested more money, which further increased the price of railway shares, until the share price collapsed. The mania reached its zenith in 1846, when 263 Acts of Parliament for setting up new railway companies were passed, with the proposed routes totalling 9,500 miles (15,300 km). About a thi... [Previous page](http://forum.0xdbfb7.com/t/scrapbook/78.md?page=3) [Next page](http://forum.0xdbfb7.com/t/scrapbook/78.md?page=5)